Context

Aptamers have gained attention, e.g. for the replacement of antibodies in research for drug discovery and diagnostic platforms.

The controlled deposition of aptamers is of interest for the development of locally bio-functionalized surfaces and sensors.

Solution

Inkjet printing

• Local bio-functionalization of sensor electrodes
• Printing process for smart sensor developments

Advanced atomic force microscopy (AFM)

• Analysis of molecular assemblies

Advantages

• Controlled local bio-functionalization of surfaces
• Advanced analysis for mastering printing process parameters in sensor developments

The developed competences are transferable to industrial biosensor developments. 

Conference presentations:

[1] Narcis Fosso, Charles Tematio, Jane Krähenbühl, Mascha Pusnik, Origène Nyanguile, and Silvia Schintke, Inkjet-printed aptamers studied by non-contact atomic force microscopy, Euro AFM-Forum, 22-24 June 2016, Geneva. - AFM image and poster prize Narcis Fosso.

[2] Narcis Fosso, Charles Tematio,Jane Krähenbühl, Enrico Condemi,Origène Nyanguile, and Silvia Schintke, Inkjet-printed aptamer assemblies for sensor developments studied by non-contact atomic force microscopy, NanoBioTech-Montreux 2016, 20th NanoBioTech Conference,7-9 November 2016, Montreux, Switzerland 

[3] Narcis Fosso, Charles Tematio, Jane Krähenbühl, Enrico Condemi, Origène Nyanguile, and Silvia Schintke, Inkjet-printing of aptamers for printable sensor developments, LOPEC 2017, LOPEC Exhibition and Conference of the Printed electro